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Semax
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Also in a protocol
Also in Recover: BPC-157 + TB-500 in one pen
One combined pen, matched to injury recovery.
Order summary
- Injectable pen, starter month
- AED 1,150
- Total
- AED 1,150
Prescription only. A DHA-licensed BioMax physician reviews your health on a call and sets your dose. No commitment, and you only pay if you go ahead.
Before you order, check who shouldn't use Semax.
- 1Free assessmentTell us your goal and health history in a few minutes.
- 2Physician callA DHA-licensed doctor confirms it’s right for you and sets your dose.
- 3Delivered to youA certified local pharmacy prepares and delivers your order.
Overview
- 15 amino acidsBased on a protein in your stomach
- Stable in stomach acidWorks as a pen or a capsule
- Studied since the 1990sFirst isolated in Zagreb, Croatia
BPC-157 is a short chain of 15 amino acids, based on a protective protein found naturally in your stomach. It is one of the most talked-about recovery peptides, popular with athletes and active people.
BPC stands for “Body Protection Compound”. In the 1990s, researchers in Zagreb, Croatia isolated a larger protective protein from human gastric juice. They then identified the 15-amino-acid section responsible for its effects and named it BPC-157. Unlike most peptides, it stays stable in stomach acid, which is why it can be taken as a capsule as well as an injection.
It was first studied as a treatment for the stomach lining. Interest in muscle and tendon recovery grew after a 2003 study in which rats’ Achilles tendons healed faster with BPC-157. Researchers describe it less as an anti-inflammatory and more as an accelerator of the body’s own repair processes.
BPC-157 is often paired with TB-500, a combination widely known online as the “Wolverine stack” because of its reputation for recovery. At BioMax you’ll find it in our Recover, Recover+, Gut Repair and Performance protocols.
Most of the research so far comes from lab and animal studies. Human studies are still at an early stage.
Uses & indications
- Tendon and ligament injuries
- Muscle strains and joint niggles
- Recovery after surgery, with your surgeon’s agreement
- Gut discomfort and support for the stomach lining
Potential benefits
- New blood supply to injured tissueLab & animal studies
- In lab and animal studies, BPC-157 activated VEGFR2, the main receptor that tells blood vessels to grow. This is angiogenesis, which brings oxygen and nutrients to damaged areas.
- Tendon and ligament repairLab & animal studies
- In tendon cells, it increased the number of growth hormone receptors and helped the cells spread and migrate. In rats, injured Achilles tendons healed faster and stronger.
- Gut lining protectionEarly human trials
- Animal studies suggest it may help protect the stomach and gut lining, including against damage from anti-inflammatory painkillers (NSAIDs). Two small early human trials tested it in ulcerative colitis.
- Healing under difficult conditionsAnimal studies
- In animal studies, healing held up even when corticosteroids were given, which normally slow repair.
- Nitric oxide signallingUnder study
- It is also being studied for its effects on the nitric oxide system, which helps control blood flow.
Typical protocol
- 500 mcgper dose
- Once a dayevening or after training
- 12 weekstypical course
- Pen or capsulecapsule for gut support
- Week 0Start your course
- Weeks 6–8Minor or recent injuries may settle
- Week 12Long-standing tendon and joint problems
- 500 mcg once a day, as a small injection under the skin using a pre-filled pen.
- A typical course is 12 weeks. Minor or recent injuries may settle in 6–8 weeks, and the course can stop once you’ve healed. Long-standing tendon and joint problems usually need the full 12 weeks.
- Often taken in the evening or after training. Injecting close to the area being treated may work best.
- For gut support, it is also available as a 500 mcg capsule, taken once a day for 8–12 weeks, with no injection needed.
- In the Recover, Recover+ and Performance protocols it comes in one combined pen with TB-500, and in Gut Repair as a combined capsule with KPV.
Your BioMax physician will set the dose and course length that suit you.
Side effects
BPC-157 is generally reported to be well tolerated.
- Most commonMild redness, itching or bruising where you inject. These usually settle with good technique and by rotating injection sites.
- OccasionalMild nausea, dizziness or headache.
Who shouldn't use it
- Active cancer or a history of cancer, because BPC-157 promotes new blood vessel growth
- Pregnancy or breastfeeding
- Anyone under 18
- Known allergy to any ingredient
Key research
The studies behind the benefits on this page. Most are lab and animal studies.
- 1Tendon repairLab & animal
Staresinic M, et al. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research, 2003.
Lab & animal - 2Tendon cell migrationLab
Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 2011.
Lab - 3Growth hormone receptorsLab
Chang CH, et al. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules, 2014.
Lab - 4Blood supplyLab & animal
Hsieh MJ, et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine, 2017.
Lab & animal - 5Nitric oxideReview
Sikiric P, et al. Stable gastric pentadecapeptide BPC 157–NO-system relation. Current Pharmaceutical Design, 2014.
Review - 6Gut lining & NSAIDsAnimal
[Author et al. Title. Journal, year.]
Animal - 7Ulcerative colitisEarly human trials
[Author et al. Title. Journal, year.]
Early human trials - 8Healing with corticosteroidsAnimal
[Author et al. Title. Journal, year.]
Animal
Often paired with
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